Last update :
19/11/2024
InfoStab
Infostab
List of drugs
List of drugs
Summary lists
Summary lists
Search for compatibilities
Search for compatibilities
Y-site compatibility table
Y-site compatibility table
References
References
Research teams
Research teams
valistab
valistab
Poster
Poster
Links
Links
Sponsors
Sponsors
Authors
Authors
User’s guide
User’s guide
Newsletter
Newsletter
References   References 859  
Type : Journal
Research teams : Oslo - The Norwegian Radium Hospital, Pharmacy Department
Authors : Karlsen J, Thonnesen HH, Olsen IR, Sollien AH, Skobba TJ.
Title : Stability of cytotoxic intravenous solutions subjected to freeze-thaw treatment.
Reference : Nor Pharm Acta ; 45: 61-67. 1983
Level of Evidence : 
Level of evidence C
Physical stability : 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
Stability indicating capability inadequately assessed
No comments for the degradation products
List of drugs
injectionDoxorubicin hydrochloride Anticancer drug
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 1,4 mg/ml -20°C Protect from light
30 Day
injectionMethotrexate sodium Anticancer drug
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 mg/ml -20°C Protect from light
30 Day
  Mentions Légales