Last update :
08/11/2024
References   References 829  
Type : Journal

Research teams : Belfast - The Queen\'s University of Belfast
Authors : Cartwright-Shamoon JM, McElnay JC, D'Arcy PF.
Title : Examination of sorption and photodegradation of amsacrine during storage in intravenous burette administration sets.
Reference : Int J Pharm ; 42: 41-46. 1988

Level of Evidence : 
Level of evidence D
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 
No visual inspection
No comments for the degradation products
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
Stability indicating capability inadequately assessed

List of drugs
injectionAmsacrine Anticancer drug
Stability in solutions Polyvinyl chloride Glucose 5% 0,15 mg/ml 19-21°C With or without light
48 Hour

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