Last update :
08/11/2024
References   References 669  
Type : Journal
Web link : https://doi.org/10.1177/106002809402800105

Research teams : Los Angeles - USC/Norris Cancer Center
Authors : Chin A, Ramakrishnan RR, Yoshimura NN, Jeong EWS, Nii LJ, DiMeglio LS.
Title : Paclitaxel stability and compatibility in polyolefin containers.
Reference : Ann Pharmacotherapy ; 28: 35-36. 1994

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
injectionPaclitaxel Anticancer drug
Stability in solutions Polyolefine NaCl 0,9% or Glucose 5% 0,3 & 1,2 mg/ml 20°C-23°C Light
48 Hour

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