Last update :
25/08/2024
References   References 4821  
Type : Journal
Web link : https:// doi.org/10.3390/pharmaceutics 16040466

Research teams : Genoa - University of Genoa, Department of Pharmacy, Genoa, Italy
Authors : Zuccari G, Villa C, Iurilli V, Barabino P, Zorzoli A, Marimpietri D, Caviglia D, Russo
Title : AmBisome® Formulations for Pediatrics: Stability, Cytotoxicity, and Cost-Effectiveness Studies.
Reference : Pharmaceutics ; 16: 466. 2024

Level of Evidence : 
Level of evidence D
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
ultraviolet spectrometry
Other methods : 
Comments : 
Stability indicating capability inadequately assessed
No visual inspection
Unencrypted results (eg graphic)
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point

List of drugs
injectionAmphotericin B liposomale Antifungal
Factors which affect stability Temperature 25°C Induces Reduced stability
Stability in solutions Glass Water for Injection 4 mg/ml 4°C Not specified
7 Day
Stability in solutions Not specified Glucose 5% 0,2 & 2 mg/ml 4°C Not specified
7 Day

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