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References   References 4728  
Type : Journal
Web link : https://doi.org/10.1016/j.jpba.2021.114209
Research teams : Grenade - Faculty of Science, Department of Analytical Chemistry
Authors : Hermosilla J, Pérez-Robles R, Salmerón-García A, Casares S, Cabeza J, Navas N.
Title : Stability study over time of clinical solutions of ziv-aflibercept prepared in infusion bags using a proper combination of physicochemical and functional strategies.
Reference : J Pharm Biomed Anal ; 203:114209. 2021
Level of Evidence : 
Level of evidence A+
Physical stability : 
Size Exclusion Chromatography Protein: Dynamic Light Scattering 
Chemical stability : 
Protein: ionic chromatography
Other methods : 
Protein: biological activity 
Comments : 
List of drugs
injectionAflibercept Anticancer drug
Stability in solutions Polyolefine Sodium chloride 0,9% 0,6 mg/ml 2-8°C Protect from light
14 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 4 mg/ml 2-8°C Protect from light
14 Day
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