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References   References 4611  
Type : Journal
Web link : https://doi.org/10.1016/j.jpha.2020.06.003
Research teams : Grenade - Faculty of Science, Department of Analytical Chemistry
Authors : Navas N, Hermosilla J, Torrente-Lopez A, Hernandez-Jimenez J, Cabeza J, Perez-Robles R, Salmeron-García A.
Title : Use of subcutaneous tocilizumab to prepare intravenous solutions for COVID-19 emergency shortage: Comparative analytical study of physicochemical quality attributes.
Reference : J Pharm Anal ;10 532e545. 2021
Level of Evidence : 
Level of evidence B
Physical stability : 
Protein: Size Exclusion Chromatography Protein: Dynamic Light Scattering 
Chemical stability : 
Protein: ionic chromatography
Protein: ultraviolet spectrometry and second derivative
Other methods : 
Comments : 
List of drugs
injectionTocilizumab Immunosuppressant
Stability in solutions Polyolefine Sodium chloride 0,9% 4 mg/mL 4°C Protect from light
24 Hour
Stability in solutions Polyolefine Sodium chloride 0,9% 6 mg/mL 4°C Protect from light
24 Hour
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