Last update :
08/11/2024
References   References 4596  
Type : Journal
Web link : https://doi.org/10.1093/ajhp/zxab195

Research teams : Barcelona - Hopital Clinic of Barcelona
Authors : Roura-Turet J, Rodriguez-Reyes M, Guerrero-Molina L, Soy-Muner D, López-Cabezas C.
Title : Stability of 5% vancomycin ophthalmic solution prepared using balanced salt solution after freezing for 90 days.
Reference : Am J Health-Syst Pharm ;78,15:444–1447 2021

Level of Evidence : 
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement Measurement of osmolality 
Comments : 

List of drugs
Eye-dropsVancomycin hydrochloride Antibiotic
Stability in solutions plastic bottle Medicine bottle for injection 500 mg
® = Pfizer
BSS solution® >> 10 mL
-20°C Not specified
90 Day
Stability in solutions plastic bottle Medicine bottle for injection 500 mg
® = Pfizer
BSS solution® >> 10 mL
5°C Not specified
30 Day

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