Last update :
19/11/2024
References   References 424  
Type : Journal

Research teams : Rochester - Bausch et Lomb Co
Authors : De NC, Alam AS, Kapoor JN.
Title : Stability of pentamidine isethionate in 5% dextrose and 0.9% sodium chloride injections.
Reference : Am J Hosp Pharm ; 43: 1486-1488. 1986

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
injectionPentamidine isetionate Antibiotic
Factors which affect stability Container Polyvinyl chlorideSodium chloride 0,9% Induces Adsorption
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 & 2 mg/ml 22°C-26°C Light
48 Hour

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