Last update :
08/11/2024
References   References 4118  
Type : Journal

Research teams : Perth - Curtin University of Technology, School of Pharmacy
Authors : Czarniak P, Boddy M, Sunderland B, Hughes J.
Title : Stability studies of lincomycin hydrochloride in aqueous solution and intravenous infusion fluids.
Reference : Drug Design Dev Ther ;10:1029-1034 2016

Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
No visual inspection
No comments for the degradation products

List of drugs
injectionLincomycin Antibiotic
Factors which affect stability pH pH = 4 Induces Enhanced stability
Stability in solutions Glass NaCl 0,9% or Glucose 5% 0,6 mg/ml 25°C Light
31 Day
Stability in solutions Glass Glucose 10% 0,6 mg/ml 25°C Light
31 Day

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