Last update :
19/11/2024
References   References 3961  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=4295

Research teams : Rochester - Mayo Clinic, Department of pharmacy
Authors : McCluskey S.V,Kirkham K,Munson J.M.
Title : Stability of Alprostadil in 0.9% Sodium Chloride Stored in Polyvinyl Chloride Containers.
Reference : Int J Pharm Compound ; 21, 2: 150-153. 2017

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Increased concentration unexplained

List of drugs
injectionAlprostadil Vasodilator
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 11 µg/ml 2-8°C Protect from light
10 Day

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