Last update :
08/11/2024
References   References 3915  
Type : Journal
Web link : http://dx.doi.org/10.2146/ajhp150677

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Myers A.L, Zhang Y, . Kawedia J.D, Shank B.R, Deaver M.A, Kramer M.A.
Title : Stability of tacrolimus injection diluted in 0.9% sodium chloride injection and stored in Excel bags
Reference : Am J Health-Syst Pharm ; 73,24: 2083-2088. 2016

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 

List of drugs
injectionTacrolimus Immunosuppressant
Stability in solutions Excel® bag Sodium chloride 0,9% 2 >> 8 µg/ml 23°C Light
9 Day
Stability in solutions Excel® bag Sodium chloride 0,9% 2 >> 8 µg/ml 4°C Protect from light
9 Day

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