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References   References 3875  
Type : Journal
Web link : http://ejhp.bmj.com/content/23/4/213.abstract
Research teams : Buenos Aires - University of Buenos Aires, Faculty of Pharmacy and Biochemistry
Authors : Estevez P, Boscolo O, Quiroga E, Penuto R.F, Buontempo F, Tripodi V, Lucangioli S.
Title : Development and stability study of glibenclamide oral liquid paediatric formulations for the treatment of permanent neonatal diabetes mellitus.
Reference : EJHP ; 23: 4: 213-218. 2016
Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
List of drugs
Oral solutionGlibenclamide Glucose-lowering
Stability in solutions Glass powder 250 mg
® = ?
xanthan gum 200 mg
methylparaben 80 mg
Propylparaben 20 mg
Distilled water >> 100 ml
25°C Protect from light
90 Day
Stability in solutions Glass tablets 250 mg
Daonil®
xanthan gum 200 mg
methylparaben 80 mg
Propylparaben 20 mg
Distilled water >> 100 ml
25°C Protect from light
90 Day
Stability in solutions Glass powder 250 mg
® = ?
Carboxymethylcellulose 800 mg
methylparaben 130 mg
Propylparaben 10 mg
Glycerin 5 g
Sodium saccharin 200 mg
Sorbitol 70% 25 g
Citric acid 100 mg
propylene glycol 600 mg
Distilled water >> 100 ml
25°C Protect from light
90 Day
Stability in solutions Glass tablets 250 mg
Daonil®
Carboxymethylcellulose 800 mg
methylparaben 130 mg
Propylparaben 10 mg
Glycerin 5 g
Sodium saccharin 200 mg
Sorbitol 70% 25 g
Citric acid 100 mg
propylene glycol 600 mg
Distilled water >> 100 ml
25°C Protect from light
90 Day
Stability in solutions Glass tablets 250 mg
Daonil®
xanthan gum 200 mg
methylparaben 80 mg
Propylparaben 20 mg
Distilled water >> 100 ml
40°C Protect from light
90 Day
Stability in solutions Glass powder 250 mg
® = ?
xanthan gum 200 mg
methylparaben 80 mg
Propylparaben 20 mg
Distilled water >> 100 ml
40°C Protect from light
90 Day
Stability in solutions Glass tablets 250 mg
Daonil®
Carboxymethylcellulose 800 mg
methylparaben 130 mg
Propylparaben 10 mg
Glycerin 5 g
Sodium saccharin 200 mg
Sorbitol 70% 25 g
Citric acid 100 mg
propylene glycol 600 mg
Distilled water >> 100 ml
40°C Protect from light
90 Day
Stability in solutions Glass powder 250 mg
® = ?
Carboxymethylcellulose 800 mg
methylparaben 130 mg
Propylparaben 10 mg
Glycerin 5 g
Sodium saccharin 200 mg
Sorbitol 70% 25 g
Citric acid 100 mg
propylene glycol 600 mg
Distilled water >> 100 ml
40°C Protect from light
90 Day
Stability in solutions Glass tablets 250 mg
Daonil®
xanthan gum 200 mg
methylparaben 80 mg
Propylparaben 20 mg
Distilled water >> 100 ml
4°C Protect from light
90 Day
Stability in solutions Glass powder 250 mg
® = ?
xanthan gum 200 mg
methylparaben 80 mg
Propylparaben 20 mg
Distilled water >> 100 ml
4°C Protect from light
90 Day
Stability in solutions Glass tablets 250 mg
Daonil®
Carboxymethylcellulose 800 mg
methylparaben 130 mg
Propylparaben 10 mg
Glycerin 5 g
Sodium saccharin 200 mg
Sorbitol 70% 25 g
Citric acid 100 mg
propylene glycol 600 mg
Distilled water >> 100 ml
4°C Protect from light
90 Day
Stability in solutions Glass powder 250 mg
® = ?
Carboxymethylcellulose 800 mg
methylparaben 130 mg
Propylparaben 10 mg
Glycerin 5 g
Sodium saccharin 200 mg
Sorbitol 70% 25 g
Citric acid 100 mg
propylene glycol 600 mg
Distilled water >> 100 ml
4°C Protect from light
90 Day
  Mentions Légales