Last update :
14/12/2024
References   References 3849  
Type : Journal
Web link : http://benthamscience.com/journals/current-pharmaceutical-biotechnology/volume/14/issue/2/page/220/

Research teams : Dublin - Royal College of Surgeons
Authors : Pabari R.M, Ryan B, Ahmad W, Ramtoola Z.
Title : Physical and structural stability of the monoclonal antibody, trastuzumab (Herceptin®), intravenous solutions.
Reference : Curr Pharm Biotech ; 14, 2: 220-225. 2013

Level of Evidence : 
Level of evidence D
Physical stability : 
Protein: Size Exclusion Chromatography Protein: Dynamic Light Scattering Visual examination Particle counting 
Chemical stability : 
Other methods : 
PH measurement 
Comments : 
Method not shown but the article refers to a validated method
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Degradation products not observed in real conditions

List of drugs
injectionTrastuzumab Anticancer drug
Stability in solutions Not specified Sodium chloride 0,9% 0.4 >> 4 mg/ml 2-8°C Not specified
28 Day

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