Last update :
19/11/2024
References   References 3825  
Type : Journal
Web link : http://www.sciencedirect.com/science/article/pii/S0378517315302842

Research teams : Bath - Department of Pharmacy & Pharmacology
Authors : Young B.L, Ali Khan M, Chapman T.J, Parry R,. Connolly M.A, Watts A.G.
Title : Evaluation of the physicochemical and functional stability of diluted REMSIMA(R) upon extended storage—A study compliant with NHS (UK) guidance.
Reference : J Pharm Pract and Res ; 496: 421-431. 2015

Level of Evidence : 
Level of evidence A+
Physical stability : 
Particle counting Protein: Size Exclusion Chromatography 
Chemical stability : 
Capillary electrophoresis
Other methods : 
PH measurement 
Comments : 
Proteins: biological activity by cell culture

List of drugs
injectionInfliximab Immunosuppressant
Stability in solutions Polyolefine Sodium chloride 0,9% 0.6 & 0.84 & 1.88 mg/ml 2-8°C Protect from light
7 Day
Biosimilar
Stability in solutions Polyolefine Sodium chloride 0,9% 0.6 & 0.84 & 1.88 mg/ml 25°C Light
7 Day
Biosimilar

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