Last update :
08/11/2024
References   References 3688  
Type : Journal
Web link : http://www.cjhp-online.ca/index.php/cjhp/article/view/1334

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Walker S.E, Charbonneau L.F, Law S.
Title : Stability of bortezomib 2.5 mg/mL in vials and syringes stored at 4°C and room temperature (23°C).
Reference : Can J Hosp Pharm ; 67, 2: 102-107 2014

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 
Degradation products detected but not quantified

List of drugs
injectionBortezomib Anticancer drug
Stability in solutions Glass Sodium chloride 0,9% 2,5 mg/ml 2-8°C Protect from light
21 Day
Stability in solutions Glass Sodium chloride 0,9% 2,5 mg/ml 23°C Light
21 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 2,5 mg/ml 2-8°C Protect from light
21 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 2,5 mg/ml 23°C Light
21 Day

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