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References   References 3651  
Type : Journal
Web link : http://pdiconnect.com/content/34/2/212.abstract
Research teams : Hobart - University of Tasmania, School of Pharmacy
Authors : Patel R.P, Shastri M.D, Bakkari M, Wanandy T, Jose M.D.
Title : Stability of the Combination of Ceftazidime and Cephazolin in Icodextrin or pH Neutral Peritoneal Dialysis Solution.
Reference : Perit Dial Int ; 34:212-218 2014
Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
No comments for the degradation products
List of drugs
injectionCefazolin sodium Antibiotic
Factors which affect stability Temperature 37°C Induces Reduced stability
injectionCeftazidime Antibiotic
Factors which affect stability Temperature 37°C Induces Reduced stability
Stability of mixtures
Polyvinyl chloride Extraneal® (Baxter) 25°C Not specified
injection Cefazolin sodium 0,125 mg/ml
injection Ceftazidime 0,125 mg/ml
24 Hour
Polyvinyl chloride Extraneal® (Baxter) 37°C Not specified
injection Cefazolin sodium 0,125 mg/ml
injection Ceftazidime 0,125 mg/ml
24 Hour
Polyvinyl chloride Extraneal® (Baxter) 4°C Protect from light
injection Cefazolin sodium 0,125 mg/ml
injection Ceftazidime 0,125 mg/ml
7 Day
  Mentions Légales