Last update :
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References   References 3344  
Type : Poster
Icone.pdf
526Ko
Research teams : Créteil - Henri Mondor University Hospital, Department of Pharmacy
Authors : Moine M, Vieillard V, Astier A, Paul M.
Title : Stabilité physicochimique du bevacizumab 5 mg/mL dilué dans le chlorure de benzalkonium 0.1 mg/mL.
Reference : ECOP Congress, Budapest, Hungary 2012
Level of Evidence : 
Level of evidence B+
Physical stability : 
Protein: Dynamic Light Scattering Protein: Size Exclusion Chromatography Protein: Thermal Aggregation Curve 
Chemical stability : 
Protein: ionic chromatography
Protein: ultraviolet spectrometry and second derivative
Other methods : 
Comments : 
Protein: no biological methods
List of drugs
Eye-dropsBevacizumab Anticancer drug
Stability in solutions Polyethylene Medicine bottle for injection 50 mg
Avastin®
Benzalkonium chloride 1 mg
NaCl 0.9% >> 10 ml
4°C Protect from light
30 Day
  Mentions Légales