Last update :
08/11/2024
References   References 3285  
Type : Journal
Web link : https://doi.org/10.1248/yakushi.129.767

Research teams : Tokyo - Nippon Medical School Hospital, Department of Pharmacy
Authors : Senoo M, Tajika K, Shimizu H, Hamada M, Dobashi Y, Dan K, Katayama S.
Title : Development of New Mixing Method of Busulfex® Injecton for the Purpose of Improvement of Medical Safety Method; The Prefilled Syringe Method.
Reference : Yakugaku Zasshi 129, 6: 767-771. 2009

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 

List of drugs
injectionBusulfan Anticancer drug
Stability in solutions Polypropylen Syringe None 6 mg/ml 4°C Not specified
4 Day

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