Last update :
19/11/2024
References   References 3274  
Type : Journal

Research teams : Rotterdam - Erasmus MC University Hospital, Department of Pharmacy
Authors : Al HadithyF.F.Y, De Goede A.L; Eckhardt M, Hanff L, Koch B.C.P.
Title : Stability of sildenafil (Revatio®) dolutions in dextrose 5%.
Reference : Intensice Care Medecine ; 37, 11: 1899. 2011

Level of Evidence : 
Level of evidence D
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
Stability indicating capability inadequately assessed
No visual inspection

List of drugs
injectionSildenafil citrate Vasodilator
Stability in solutions Polypropylen Syringe Glucose 5% 0,067 mg/ml 25°C Not specified
7 Day
Stability in solutions Polypropylen Syringe Glucose 5% 0,067 mg/ml 37°C Not specified
7 Day
Stability in solutions Polypropylen Syringe Glucose 5% 0,667 mg/ml 25°C Not specified
7 Day
Stability in solutions Polypropylen Syringe Glucose 5% 0,667 mg/ml 37°C Not specified
7 Day

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