Last update :
27/11/2024
References   References 3228  
Type : Journal
Web link : http://www.ajhp.org/content/68/18/1723.abstract

Research teams : Ottawa - The Ottawa Hospital, department of Pharmacy
Authors : Frenette AJ, MacLean RD, Williamson D, Marsolais P, . Donnelly RF
Title : Stability of levothyroxine injection in glass, polyvinyl chloride, and polyolefin containers
Reference : Am J Health-Syst Pharm ;68:1723-1728. 2011

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
injectionLevothyroxine Hormone
Stability in solutions Glass Glucose 5% 1 µg/ml 19-25°C
24 Hour
Stability in solutions Polyolefine Glucose 5% 1 µg/ml 19-25°C
24 Hour

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