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References   References 3195  
Type : Journal
Research teams : Plymouth - Derriford Hospital,Department of Pharmacy
Authors : MacLeod S, Sewell G.
Title : Physical and chemical stability of docetaxel infusions.
Reference : EJHP ; 17, 2: 39-43. 2011
Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
PH measurement Mass balance 
Comments : 
Degradation products not observed in real conditions
List of drugs
injectionDocetaxel Anticancer drug
Stability in solutions Polyolefine NaCl 0,9% or Glucose 5% 0,3 mg/ml 2-8°C Protect from light
56 Day
Stability in solutions Polyolefine NaCl 0,9% or Glucose 5% 0,3 mg/ml 25°C Protect from light
56 Day
Stability in solutions Polyolefine NaCl 0,9% or Glucose 5% 0,7 mg/ml 2-8°C Protect from light
56 Day
Stability in solutions Polyolefine NaCl 0,9% or Glucose 5% 0,7 mg/ml 25°C Protect from light
56 Day
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