Last update :
19/11/2024
References   References 3163  
Type : Journal

Research teams : Dagenham - Sanofi-Aventis, Analytical Development
Authors : Acott SR, Hart M.
Title : Physical and chemical stability of Taxotere 1-vial 20mg/mL infusion solution following refrigerated storage.
Reference : EJHP ; 16, 5: 26-28. 2010

Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Method not shown but used to deposit authorization to market
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point

List of drugs
injectionDocetaxel Anticancer drug
Stability in solutions Polyethylene Sodium chloride 0,9% 0,8 mg/ml 5°C Protect from light
7 Day

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