Last update :
19/11/2024
References   References 3140  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=3202

Research teams : West Point - Merck and Co
Authors : Tsiouris M, Ulmer M, Yurcho J F, Hooper K L, Gui M.
Title : Stability and Compatibility of Reconstituted Caspofungin in Select Elastomeric Infusion Device.
Reference : Int J Pharm Compound ; 14, 5 : 436-439. 2010

Level of Evidence : 
Level of evidence D
Physical stability : 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
No visual inspection
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Degradation products not observed in real conditions

List of drugs
injectionCaspofungin acetate Antifungal
Stability in solutions Polyisoprene elastomer Sodium chloride 0,9% 0,2 >> 0,5 mg/ml 2-8°C Not specified
14 Day
Stability in solutions Polyisoprene elastomer Sodium chloride 0,9% 0,2 >> 0,5 mg/ml 25°C Not specified
60 Hour

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