Last update :
08/11/2024
References   References 303  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/55/2/154

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Walker SE, Gray S, Schmidt B.
Title : Stability of reconstituted indomethacin sodium trihydrate in original vials and polypropylene syringes.
Reference : Am J Health-Syst Pharm ; 55: 154-158. 1998

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products detected but not quantified

List of drugs
injectionIndomethacin sodium trihydrate Anti-inflammatory
Stability in solutions Glass Water for Injection 0,5 mg/ml 2-6°C Protect from light
14 Day
Stability in solutions Glass Water for Injection 0,5 mg/ml 21°C-25°C Light
12 Day
Stability in solutions Polypropylen Syringe Water for Injection 0,5 mg/ml 2-6°C Protect from light
14 Day
Stability in solutions Polypropylen Syringe Water for Injection 0,5 mg/ml 21°C-25°C Light
14 Day

  Mentions Légales