Last update :
14/12/2024
References   References 282  
Type : Journal

Research teams : Birmingham - Princeton Baptist Medical Center, Department of Pharmacy
Authors : Rivers TE, Webster AA.
Title : Stability of ceftizoxime sodium, ceftriaxone sodium, and ceftazidime with metronidazole in ready-to-use metronidazole bags.
Reference : Am J Health-Syst Pharm ; 52: 2568-2570. 1995

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 

List of drugs
injectionCeftazidime Antibiotic
Compatible 10 mg/ml + injectionMetronidazole 5 mg/ml + None
injectionCeftizoxime sodium Antibiotic
Compatible 10 mg/ml + injectionMetronidazole 5 mg/ml + None
injectionCeftriaxone disodium Antibiotic
Compatible 10 mg/ml + injectionMetronidazole 5 mg/ml + None
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionCeftazidime 10 mg/ml + None
Compatible 5 mg/ml + injectionCeftizoxime sodium 10 mg/ml + None
Compatible 5 mg/ml + injectionCeftriaxone disodium 10 mg/ml + None
Stability of mixtures
Polyvinyl chloride None 8°C Not specified
injection Metronidazole 5 mg/ml
injection Ceftizoxime sodium 10 mg/ml
72 Hour
Polyvinyl chloride None 8°C Not specified
injection Metronidazole 5 mg/ml
injection Ceftriaxone disodium 10 mg/ml
72 Hour
Polyvinyl chloride None 8°C Not specified
injection Metronidazole 5 mg/ml
injection Ceftazidime 10 mg/ml
72 Hour

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