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References   References 2659  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=3114
Research teams : Cincinnati - University of Cincinnati Medical Center, The James L. Winkle College of Pharmacy
Authors : Khondkar D, Chopra P, McArter JP, Rosen JA, Li SK.
Title : Chemical stability of hydromorphone hydrochloride in patient-controlled analgesia injector.
Reference : Int J Pharm Compound ; 14, 2: 160-164. 2010
Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
High Performance Liquid Chromatography - mass spectrometry (HPLC-MS)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
injectionHydromorphone hydrochloride Analgesic
Stability in solutions Not specified Sodium chloride 0,9% 0,2 mg/ml 20°C With or without light
112 Day
Stability in solutions Not specified Sodium chloride 0,9% 0,2 mg/ml 35°C Protect from light
112 Day
Stability in solutions Not specified Sodium chloride 0,9% 0,2 mg/ml 5°C Protect from light
112 Day
  Mentions Légales