Last update :
14/12/2024
References   References 2649  
Type : Journal
Web link : https://doi.org/10.1016/S0378-5173(01)00961-9

Research teams : Clermont-Ferrand - University Hospital Gabriel Monpied, Department of Pharmacy
Authors : Sautou-Miranda V, Libert F, Grand-Boyer A, Gellis C, Chopineau J.
Title : Impact of deep freezing on the stability of 25 mg/ml vancomycin ophtalmic solutions.
Reference : Int J Pharm ; 234, 1-2: 205-212. 2002

Level of Evidence : 
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
Degradation products not observed in real conditions

List of drugs
Eye-dropsVancomycin hydrochloride Antibiotic
Stability in solutions Glass Medicine bottle for injection 125 mg
Vancomycine Dakota®
Dextrose 5% >> 5 ml
-20°C Protect from light
90 Day

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