Last update :
19/11/2024
References   References 2634  
Type : Journal

Research teams : Columbus - The Ohio State University Hospitals, Department of Pharmacy
Authors : Nahata MC, Morosco RS, Hipple TF.
Title : Stability of metolazone in a liquid dosage form.
Reference : Hosp Pharm ; 32: 691-693. 1997

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
Oral solutionMetolazone Diuretic
Factors which affect stability Temperature Increase Induces Degradation
Stability in solutions Glass tablets 6.25 mg
®=∞ (Fisons corporation)
Methylcellulose 1% / Simple syrup (1:1) >> 25 ml
25°C Not specified
7 Day
Stability in solutions Glass tablets 6.25 mg
®=∞ (Fisons corporation)
Methylcellulose 1% / Simple syrup (1:1) >> 25 ml
4°C Protect from light
90 Day
Stability in solutions plastic bottle tablets 6.25 mg
®=∞ (Fisons corporation)
Methylcellulose 1% / Simple syrup (1:1) >> 25 ml
25°C Not specified
7 Day
Stability in solutions plastic bottle tablets 6.25 mg
®=∞ (Fisons corporation)
Methylcellulose 1% / Simple syrup (1:1) >> 25 ml
4°C Protect from light
90 Day

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