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References   References 245  
Type : Journal
Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : Phaypradith S, Vigneron J, Perrin A, Durney-Archeray MJ, Hoffman MA, Hoffman M.
Title : Stability of ganciclovir sodium (Cymevan*) after dilution in PVC infusions and polypropylene syringes.
Reference : J Pharm Belg ; 47: 494-498. 1992
Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions
No visual inspection
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
List of drugs
injectionGanciclovir sodium Antiviral
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,28 & 1,4 mg/ml -20°C Protect from light
365 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,28 & 1,4 mg/ml 25°C Not specified
8 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,28 & 1,4 mg/ml 4°C Protect from light
80 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1,4 & 7 mg/ml -20°C Protect from light
365 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1,4 & 7 mg/ml 25°C Not specified
8 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1,4 & 7 mg/ml 4°C Protect from light
80 Day
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