Last update :
18/07/2024
References   References 2329  
Type : Journal

Research teams : Ottawa - The Ottawa Hospital, department of Pharmacy
Authors : Donnely R.F, Willman E, Andolfatto G.
Title : Stability of Ketamine-Propofol mixtures for procedural sedation and analgesia in the emergency department.
Reference : Can J Hosp Pharm ; 61, 6: 426-430. 2008

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionKetamine hydrochloride General anesthetic
Compatible 10 mg/ml + injectionPropofol 10 mg/ml + None
Compatible 3.3 mg/ml + injectionPropofol 6.7 mg/ml + None
injectionPropofol General anesthetic
Compatible 10 mg/ml + injectionKetamine hydrochloride 10 mg/ml + None
Compatible 6.7 mg/ml + injectionKetamine hydrochloride 3.3 mg/ml + None
Stability of mixtures
Polypropylen Syringe None 23°C Light
injection Ketamine hydrochloride 5,2 mg/ml conflicting data
injection Propofol 4,9 mg/ml conflicting data
3 Hour
Polypropylen Syringe None 23°C Light
injection Ketamine hydrochloride 3,3 mg/ml conflicting data
injection Propofol 6,8 mg/ml conflicting data
3 Hour

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