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Internet legătură într- : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=2736

Echipe de cercetare : Houston - M.D.Anderson Cancer Center
Autor : Trusley C, Ben M, Kupiec TC, Trissel LA.
titlu : Compatibility and stability of palonosetron hydrochloride with four neuromuscular blocking agents during simulated Y-site administration.
Référence : Int J Pharm Compound ; 12, 2: 156-160. 2008

Nivelul dovezii : 
Nivel de evidență A+
stabilitatea fizică : 
Examinare vizuala Turbidimetrie Numararea particulelor 
Stabilitate chimică : 
Cromatografia de lichide de inalta performanta cu detector de diode
Stabilitate definită ca si 95% din concentrația inițială
alte metode : 
Comentarii : 

Listele
InjectabilCisatracurium besylate Curarizant
Compatibil 0,5 mg/ml + InjectabilPalonosetron hydrochloride 50 µg/ml + Glucoza 5%
InjectabilPalonosetron hydrochloride Antiemetic
Compatibil 50 µg/ml + InjectabilCisatracurium besylate 0,5 mg/ml + Glucoza 5%
Compatibil 50 µg/ml + InjectabilRocuronium bromide 1 mg/ml + Glucoza 5%
Compatibil 50 µg/ml + InjectabilSuxamethonium chloride 2 mg/ml + Glucoza 5%
Compatibil 50 µg/ml + InjectabilVecuronium bromide 1 mg/ml + Glucoza 5%
InjectabilRocuronium bromide Curarizant
Compatibil 1 mg/ml + InjectabilPalonosetron hydrochloride 50 µg/ml + Glucoza 5%
InjectabilSuxamethonium chloride Curarizant
Compatibil 2 mg/ml + InjectabilPalonosetron hydrochloride 50 µg/ml + Glucoza 5%
InjectabilVecuronium bromide Curarizant
Compatibil 1 mg/ml + InjectabilPalonosetron hydrochloride 50 µg/ml + Glucoza 5%
Stabilitatea in amestec
sticla Glucoza 5% 25°C Neprecizat
Injectabil Cisatracurium besylate 0.26 mg/ml
Injectabil Palonosetron hydrochloride 25.4 µg/ml
4 Ora
sticla Glucoza 5% 25°C Neprecizat
Injectabil Rocuronium bromide 0.5 mg/ml
Injectabil Palonosetron hydrochloride 25 µg/ml
4 Ora
sticla Glucoza 5% 25°C Neprecizat
Injectabil Palonosetron hydrochloride 26 µg/ml
Injectabil Suxamethonium chloride 1.05 mg/ml
4 Ora
sticla Glucoza 5% 25°C Neprecizat
Injectabil Palonosetron hydrochloride 25.6 µg/ml
Injectabil Vecuronium bromide 0.5 mg/ml
4 Ora

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