Last update :
14/12/2024
References   References 2221  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/64/23/2480

Research teams : Ann Arbor - University of Michigan, College of Pharmacy
Authors : Cober M.P, Johnson C.E.
Title : Stability of 70% alcohol solutions in polypropylene syringes for use in ethanol-lock therapy.
Reference : Am J Health-Syst Pharm ; 64, 23: 2480-2482. 2007

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 

List of drugs
injectionEthanol Various
Stability in solutions Polypropylen Syringe Water for Injection 70 % 23-25°C Not specified
14 Day
Stability in solutions Polypropylen Syringe Water for injection + antibacterial 70 % 23-25°C Not specified
14 Day
Incompatible 70 % + injectionHeparin sodium 1000 UI/ml + Water for Injection
Incompatible 70 % + injectionHeparin sodium 10 UI/ml + Water for Injection
Incompatible 70 % + injectionHeparin sodium 1000 UI/ml + Water for injection + antibacterial
Incompatible 70 % + injectionHeparin sodium 10 UI/ml + Water for injection + antibacterial
Incompatible 70 % + injectionSodium citrate 7.3 mg/ml + Water for Injection
Incompatible 70 % + injectionSodium citrate 7.3 mg/ml + Water for injection + antibacterial
injectionHeparin sodium Anticoagulant
Incompatible 1000 UI/ml + injectionEthanol 70 % + Water for Injection
Incompatible 10 UI/ml + injectionEthanol 70 % + Water for Injection
Incompatible 1000 UI/ml + injectionEthanol 70 % + Water for injection + antibacterial
Incompatible 10 UI/ml + injectionEthanol 70 % + Water for injection + antibacterial
injectionSodium citrate Electrolyte
Incompatible 7.3 mg/ml + injectionEthanol 70 % + Water for Injection
Incompatible 7.3 mg/ml + injectionEthanol 70 % + Water for injection + antibacterial

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