Last update :
08/11/2024
References   References 2027  
Type : Journal
Web link : http://www.cshp.ca/dms/dmsView/1_Abs2.pdf

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Walker SE, Shirley L, Puodziunas A.
Title : Simulation of Y-site compatibility of irinotecan and leucovorin at room temperature in 5% dextrose in water in 3 different containers.
Reference : Can J Hosp Pharm ; 58: 212-222. 2005

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionFolinate calcium Cytoprotective
Incompatible 3.6 mg/ml + injectionIrinotecan 0.32 mg/ml + Glucose 5%
Compatible 0.27 >> 0.94 mg/ml + injectionIrinotecan 0.30 >> 0.59 mg/ml + Glucose 5%
injectionIrinotecan Anticancer drug
Incompatible 0.32 mg/ml + injectionFolinate calcium 3.6 mg/ml + Glucose 5%
Compatible 0.30 >> 0.59 mg/ml + injectionFolinate calcium 0.27 >> 0.94 mg/ml + Glucose 5%

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