Last update :
19/11/2024
References   References 2012  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/62/19/2001

Research teams : Nimes - Caremeau Hospital, Pharmacy Department
Authors : Bougouin C, Thelcide C, Crespin-Maillard F, Maillard C, Kinowski JM, Favier M.
Title : Compatibility of ondansetron hydrochloride and methylprednisolone sodium succinate in multilayer polyolefin containers.
Reference : Am J Health-Syst Pharm ; 62: 2001-2005. 2005

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 2,4 mg/ml + injectionOndansetron hydrochloride 0,16 mg/ml + Sodium chloride 0,9%
Compatible 2,4 mg/ml + injectionOndansetron hydrochloride 0,16 mg/ml + Glucose 5%
injectionOndansetron hydrochloride Antiemetic
Compatible 0,16 mg/ml + injectionMethylprednisolone sodium succinate 2,4 mg/ml + Sodium chloride 0,9%
Compatible 0,16 mg/ml + injectionMethylprednisolone sodium succinate 2,4 mg/ml + Glucose 5%
Stability of mixtures
Polyolefine NaCl 0,9% or Glucose 5% 20°C-25°C Light
injection Ondansetron hydrochloride 0,16 mg/ml
injection Methylprednisolone sodium succinate 2,4 mg/ml
24 Hour
Polyolefine NaCl 0,9% or Glucose 5% 4°C Not specified
injection Ondansetron hydrochloride 0,16 mg/ml
injection Methylprednisolone sodium succinate 2,4 mg/ml
48 Hour

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