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References   References 1988  
Type : Journal
Research teams : Chicago - University of Illinois, College of Pharmacy
Authors : Sprandel KA, Styrszula DE, Deyo K, Sibley C, Rodvold KA.
Title : Stability and compatibility of levofloxacin and metronidazole during simulated and actual Y-site administration.
Reference : Am J Health-Syst Pharm ; 62: 88-92. 2005
Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
injectionLevofloxacine Antibiotic
Compatible 5 mg/ml + injectionMetronidazole 5 mg/ml + None
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionLevofloxacine 5 mg/ml + None
Stability of mixtures
Glass None 23°C Light
injection Metronidazole 2,5 mg/ml
injection Levofloxacine 2,5 mg/ml
3 Hour
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