Last update :
19/11/2024
References   References 1985  
Type : Journal

Research teams : La Plata - Facultad de Ciencias Exactas
Authors : Volonté MG, Valora PD, Congolani A, Ferrara M.
Title : Stability of ibuprofen in injection solutions.
Reference : Am J Health-Syst Pharm ; 62: 630-633. 2005

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products identified and quantified

List of drugs
injectionIbuprofen lysinate Anti-inflammatory
Factors which affect stability Storage Light Induces Degradation
Stability in solutions Not specified Water for Injection 1 & 4 mg/ml 25°C Light
15 Day
Stability in solutions Not specified Water for Injection 27,5 mg/ml 25°C With or without light
15 Day
Stability in solutions Not specified NaCl 0,9% or Glucose 5% 1 & 4 mg/ml 25°C Light
15 Day

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