Last update :
19/11/2024
References   References 1981  
Type : Journal

Research teams : Paris - European University Hospital Georges Pompidou
Authors : Certain E, Beteta F, Goudou-Sinha C, Darbord JC, Prognon P, Jacquot C.
Title : Stability of i.v. mycophenolate mofetil in 5% dextrose injection in polyvinyl chloride infusion bags.
Reference : Am J Health-Syst Pharm ; 59: 2434-2439. 2002

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
injectionMycophenolate mofetil Immunosuppressant
Factors which affect stability Storage Light Induces Degradation
Factors which affect stability Solvent Sodium chloride 0,9% Induces Precipitation
Stability in solutions Polyvinyl chloride Glucose 5% 1 & 10 mg/ml 25°C Not specified
7 Day
Stability in solutions Polyvinyl chloride Glucose 5% 1 & 10 mg/ml 4°C Not specified
7 Day
Incompatible + Sodium chloride 0,9%

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