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References   References 1962  
Type : Journal
Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Hecq JD, Boitquin L, Evrard JM, Vanbeckbergen D, Jamart J, Galanti L.
Title : Long term stability of sufentanyl citrate with levobupivacaine hydrochloride in 0.9% sodium chloride infusion P.V.C bags at 4°C.
Reference : Pharmakon ; 36, 1: 8-14. 2004
Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed
List of drugs
injectionLevobupivacaine hydrochloride Local anesthetic
Compatible 1.25 mg/ml + injectionSufentanil citrate 0.001 mg/ml + Sodium chloride 0,9%
injectionSufentanil citrate Analgesic
Compatible 0.001 mg/ml + injectionLevobupivacaine hydrochloride 1.25 mg/ml + Sodium chloride 0,9%
Stability of mixtures
Polyvinyl chloride Sodium chloride 0,9% 4°C Protect from light
injection Sufentanil citrate 0,001 mg/ml
injection Levobupivacaine hydrochloride 1,25 mg/ml
58 Day
  Mentions Légales