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08/11/2024
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References 1950
Type :
Journal
Web link :
http://opp.sagepub.com/cgi/content/abstract/10/4/191
Research teams :
Houston - M.D.Anderson Cancer Center
Authors :
Trissel LA, Yanping Z.
Title :
Physical and chemical stability of palonosetron HCl with cisplatin, carboplatin and oxaliplatin during simulated Y-site administration.
Reference :
J Oncol Pharm Practice ; 10: 191-195. 2004
Level of Evidence :
Physical stability :
Chemical stability :
Other methods :
Comments :
Degradation products not observed in real conditions
List of drugs
Carboplatin
5 mg/ml
+
Palonosetron hydrochloride
50 µg/ml
+
Cisplatin
0,5 mg/ml
+
Palonosetron hydrochloride
50 µg/ml
+
Oxaliplatin
0,5 mg/ml
+
Palonosetron hydrochloride
50 µg/ml
+
Palonosetron hydrochloride
50 µg/ml
+
Carboplatin
5 mg/ml
+
50 µg/ml
+
Cisplatin
0,5 mg/ml
+
50 µg/ml
+
Oxaliplatin
0,5 mg/ml
+
?
Palonosetron hydrochloride
25 µg/ml
Cisplatin
0,25 mg/ml
4
?
Carboplatin
2,5 mg/ml
Palonosetron hydrochloride
25 µg/ml
4
?
Palonosetron hydrochloride
25 µg/ml
Oxaliplatin
0,25 mg/ml
4
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