Last update :
14/12/2024
References   References 1922  
Type : Journal

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Zhang Y.
Title : Stability of methylprednisolone sodium succinate in autodose infusion system bags.
Reference : J Am Pharm Assoc ; 42: 868-870. 2002

Level of Evidence : 
Level of evidence B+
Physical stability : 
Visual examination Turbidimetry Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 

List of drugs
injectionMethylprednisolone sodium succinate Anti-inflammatory
Stability in solutions Ethylene vinyl acetate Sodium chloride 0,9% 1 mg/ml 4°C Protect from light
7 Day
Stability in solutions Ethylene vinyl acetate Sodium chloride 0,9% 10 mg/ml 23°C Protect from light
2 Day
Stability in solutions Ethylene vinyl acetate Sodium chloride 0,9% 10 mg/ml 4°C Protect from light
21 Day

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