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References   References 1908  
Type : Journal
Web link : https://www.sciencedirect.com/science/article/pii/S0885392404001769
Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Boitquin L, Hecq JD, Evrard JM, Vanbeckbergen D, Jamart J, Galanti L.
Title : Long-term stability of sufentanil citrate with levobupivacaine hydrochloride in 0.9% sodium chloride infusion PVC bags at 4°C.
Reference : J Pain Symptom Manage ; 28, 1: 4-6. 2004
Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
injectionLevobupivacaine hydrochloride Local anesthetic
Compatible 1,25 mg/ml + injectionSufentanil citrate 0,001 mg/ml + Sodium chloride 0,9%
injectionSufentanil citrate Analgesic
Compatible 0,001 mg/ml + injectionLevobupivacaine hydrochloride 1,25 mg/ml + Sodium chloride 0,9%
Stability of mixtures
Polyvinyl chloride Sodium chloride 0,9% 4°C Not specified
injection Sufentanil citrate 0,001 mg/ml
injection Levobupivacaine hydrochloride 1,25 mg/ml
58 Day
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