Last update :
19/11/2024
References   References 1907  
Type : Journal
Web link : http://www.factsandcomparisons.com/HospitalPharm/?id=1000132

Research teams : Stockton - University of the Pacific, Department of Pharmaceutics and Medical Chemistry
Authors : Burger DE, Caldwell JW.
Title : Sustaining treatment of coccidioidal meningitidis by extending the stability of amphotericin B.
Reference : Hosp Pharm ; 39: 554-557. 2004

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination Turbidimetry Particle counting 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed
Method not shown but the article refers to a validated method
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Degradation products not observed in real conditions

List of drugs
injectionAmphotericin B Antifungal
Stability in solutions Polyvinyl chloride Glucose 5% 0,1 mg/ml 4°C Protect from light
15 Day

  Mentions Légales