Last update :
19/11/2024
References   References 1889  
Type : Journal
Web link : http://www.sciencedirect.com/science/article/pii/S0378517315300405

Research teams : Angers - University Hospital of Angers, Pharmacy Department
Authors : Briota Th, Vrignaud S, Lagarce F.
Title : Stability of micafungin sodium solutions at different concentrations in glass bottles and syringes.
Reference : Int J Pharm ; 492 : 137?140. 2015

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
injectionMicafungin Antifungal
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0.5 mg/ml 23-27°C Protect from light
15 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 1 mg/ml 23-27°C Protect from light
15 Day

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