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References   References 1827  
Type : Journal
Web link : http://www.unboundmedicine.com/medline/ebm/record/2126037/abstract/Chemical_stability_of_the_antitumor_drug_mitomycin_C_in_solutions_for_intravesical_instillation_
Research teams : Utrecht - Faculty of pharmacy, State university of Utrecht
Authors : Beijnen JH, Van Gijn R, Underberg WJM.
Title : Chemical stability of the antitumor mitomycin C in solutions for intravesical instillation.
Reference : J Parenter Sci Technol ; 44: 332-335. 1990
Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
No comments for the degradation products
List of drugs
injectionMitomycin Anticancer drug
Factors which affect stability Storage 4°C[ > 0,6 mg / ml] Induces Precipitation
Stability in solutions Glass Water for Injection 1 mg/ml 25°C Not specified
24 Hour
conflicting data
Stability in solutions Not specified Water for Injection 0,6 mg/ml 4°C Protect from light
4 Day
Stability in solutions Not specified Water for Injection 0,6 & 0,8 mg/ml 25°C Protect from light
4 Day
conflicting data
  Mentions Légales