Last update :
19/11/2024
References   References 180  
Type : Journal

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Zhang Y, Trissel LA, Martinez JF, Gilbert DL.
Title : Stability of metoclopramide hydrochloride in plastic syringes.
Reference : Am J Health-Syst Pharm ; 53: 1300-1302. 1996

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 

List of drugs
injectionMetoclopramide hydrochloride Antiemetic
Factors which affect stability Temperature -20°C Induces Precipitation
Stability in solutions Polypropylen Syringe None 5 mg/ml 23°C Not specified
60 Day
Stability in solutions Polypropylen Syringe None 5 mg/ml 32°C Not specified
7 Day
Stability in solutions Polypropylen Syringe None 5 mg/ml 4°C Protect from light
90 Day

  Mentions Légales