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References   References 18  
Type : Journal
Research teams : Los Angeles - University of Southern california, School of Pharmacy
Authors : Pompilio FM, Fox JL, Inagaki K, Burm JP, Jhee S, Gill MA.
Title : Stability of ranitidine hydrochloride with ondansetron hydrochloride or fluconazole during simulated Y-site administration.
Reference : Am J Hosp Pharm ; 51: 391-394. 1994
Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
List of drugs
injectionFluconazole Antifungal
Compatible 2 mg/ml + injectionRanitidine hydrochloride 0,5 & 2 mg/ml + Glucose 5%
injectionOndansetron hydrochloride Antiemetic
Compatible 0,03 >> 0,3 mg/ml + injectionRanitidine hydrochloride 0,5 & 2 mg/ml + Glucose 5%
injectionRanitidine hydrochloride Antihistamine (H2)
Compatible 0,5 & 2 mg/ml + injectionFluconazole 2 mg/ml + Glucose 5%
Compatible 0,5 & 2 mg/ml + injectionOndansetron hydrochloride 0,03 >> 0,3 mg/ml + Glucose 5%
Stability of mixtures
Glass Glucose 5% 25°C Light
injection Ranitidine hydrochloride 0,5 & 2 mg/ml
injection Ondansetron hydrochloride 0,03 & 0,3 mg/ml
4 Hour
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