Last update :
08/11/2024
References   References 1748  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=1288

Research teams : Taipei - National Defense Medical Center, School of Pharmacy
Authors : Wang DP, Wang MT, Wong CY, Lee DKT.
Title : Compatibility of vancomycin hydrochloride and famotidine in 5% dextrose injection.
Reference : Int J Pharm Compound ; 1: 354-355. 1997

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
No comments for the degradation products

List of drugs
injectionFamotidine Antihistamine (H2)
Compatible 0,2 mg/ml + injectionVancomycin hydrochloride 5 mg/ml + Glucose 5%
injectionVancomycin hydrochloride Antibiotic
Compatible 5 mg/ml + injectionFamotidine 0,2 mg/ml + Glucose 5%
Stability of mixtures
Not specified Glucose 5% 25°C Protect from light
injection Vancomycin hydrochloride 0,5 mg/ml
injection Famotidine 0,2 mg/ml
14 Day
Not specified Glucose 5% 4°C Protect from light
injection Vancomycin hydrochloride 0,5 mg/ml
injection Famotidine 0,2 mg/ml
14 Day

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