Last update :
19/11/2024
References   References 1604  
Type : Journal

Research teams : Paris - University Hospital Sainte-Anne, Department of Clinical Pharmacy
Authors : Gury C, Dolizy I, Aymard N, Sellali Y, Rochet S.
Title : Stability of citalopram hydrochloride in polyvinyl chloride bag for I.V. solutions and compatibility in the presence of dipotassium clorazepate.
Reference : Eur Hosp Pharm ; 7: 11-14. 2001

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - fluorescence detector
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed
Repeatability / reproducibility / standard range: results not provided or results outside specified values

List of drugs
injectionCitalopram Antidepressant
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,16 mg/ml 20°C-25°C Light
24 Hour
injectionClorazepate di potassium Anxiolytic
Stability of mixtures
Polyvinyl chloride NaCl 0,9% or Glucose 5% 20°C-25°C Light
injection Citalopram 0,16 mg/ml
injection Clorazepate di potassium 0,08 mg/ml
4 Hour

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