Last update :
19/11/2024
References   References 1455  
Type : Journal

Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : Demoré B, Raffy F, Commun N, Vigneron J, Hoffman MA, Hoffman M.
Title : Etude de la stabilité de deux benzamides antiémétiques en poches PVC de chlorure de sodium 0.9% et de glucose 5% sur une période de 5 mois.
Reference : J Pharm Clin ; 14: 178-179. 1995

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
injectionAlizapride hydrochloride Antiemetic
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,5 & 3 mg/ml -20°C Protect from light
150 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,5 & 3 mg/ml 4°C Protect from light
150 Day
injectionMetoclopramide hydrochloride Antiemetic
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,3 & 1 mg/ml -20°C Protect from light
150 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,3 & 1 mg/ml 4°C Protect from light
150 Day

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