Last update :
19/11/2024
References   References 125  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/53/13/1576

Research teams : Athens - University of Georgia, College of Pharmacy
Authors : Chernin EL, Stewart JT, Smiler B.
Title : Stability of thiopental sodium and propofol in polypropylene syringes at 23 and 4°C.
Reference : Am J Health-Syst Pharm ; 53: 1576-1579. 1996

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
injectionPropofol General anesthetic
Compatible 5 mg/ml + injectionThiopental sodium 12,5 mg/ml + None
injectionThiopental sodium General anesthetic
Compatible 12,5 mg/ml + injectionPropofol 5 mg/ml + None
Stability of mixtures
Polypropylene None 23°C Light
injection Thiopental sodium 12,5 mg/ml
injection Propofol 5 mg/ml
5 Day
Polypropylene None 4°C Protect from light
injection Thiopental sodium 12,5 mg/ml
injection Propofol 5 mg/ml
13 Day

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